Modified hodge test pdf

See discussions, stats, and author profiles for this publication at. The modified hodge test for suspected carbapenemase production in. Hodge hartford faculty scholar in geriatric social work school of social work college of public programs, arizona state university mail code 3920, 411 n. Accurate detection of carbapenemaseproducing gramnegative bacilli is of utmost importance for the control of nosocomial spread and the initiation of appropriate antimicrobial therapy. The modified hodge test mht employs reagents readily available in most laboratories but involves subjective result interpretation and suffers from both falsepositive results particularly with enterobacter spp. This study was designed to determine in vitro efficacy of modified hodge test for detection of carbapenemase production in gram negative rods. Its sensitivity is low for ndm1 producers 50% but is increased to 85. The modified hodge test mht, a carbapenem inactivation assay, has shown poor sensitivity in detecting the. This study was designed to determine in vitro efficacy of modified hodge test for detection of. Modified hodge test mht has been suggested as screening tests for carbapenemases. Cloverleaf test modified hodge test for detecting carbapenemase.

Resistance among bacterial isolates is the leading cause of increased mortality and morbidity worldwide. The modified hodge test has an excellent sensitivity for detecting enterobacterial isolates producing ambler class a kpc and class d oxa48 carbapenemases. A simple and effective test for detection of carbapenemase production. Modified hodge test, disc diffusion, carbapenemases. You first do you screen for carbapenemases rectal screening ast results only do you use chromogenic media for carbapenemase screens how many use the modified hodge test. Modified carbapenem inactivation method for phenotypic. Modified hodge test or pcr also include antibiotic susceptibility results and carbapenemase testing method and results. The hodge test performed poorly for carbapenemase detection. The modified hodge test has an excellent sensitivity for detecting. Carbapenems once thought to be effective are becoming ineffective mostly due to the emergence of carbapenemase.